Cavaliers vs. Knicks Game 2 Predictions, Odds & Stats – May 21

New York Knicks v Washington Wizards

Photo: Jess Rapfogel / Getty Images Sport / Getty Images

The New York Knicks are 5.5-point favorites in Game 2 of the Eastern Conference Finals against the Cleveland Cavaliers at Madison Square Garden on Thursday, tipping off at 8 p.m. ET on ESPN. The Knicks have a 1-0 lead in the series.

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Listen to the game on ESPN New York

Cavaliers vs. Knicks Predictions for Thursday

Our computer projections model for this contest expects a final result of Knicks 118, Cavaliers 111.

  • Moneyline Pick: Knicks (-213)
  • Total Pick: Over 215.5 (computer predicts 229.3 points)
  • Pick ATS: Knicks (-5.5)

Recent Cavaliers vs. Knicks Matchups

Knicks vs Cavaliers (Recent Matchups)
Date Favorite Spread Total Favorite Moneyline Underdog Moneyline Result
5/19/2026 Knicks -6.5 218.5 -240 +197 115-104 NY
2/24/2026 Cavaliers -4.5 231.5 -170 +142 109-94 CLE
12/25/2025 Knicks -5.5 240.5 -218 +180 126-124 NY
10/22/2025 Cavaliers -1.5 229 -126 +106 119-111 NY
4/11/2025 Knicks -2 223.5 -149 +125 108-102 CLE
4/2/2025 Cavaliers -10.5 231.5 -515 +389 124-105 CLE
2/21/2025 Cavaliers -7.5 241.5 -296 +238 142-105 CLE
10/28/2024 Knicks -3 222.5 -142 +121 110-104 CLE

Knicks 2025-26 Betting Trends

  • New York is 43-39-0 against the spread this season.
  • The Knicks are 25-17 against the spread when favored by 5.5 points or more this season.
  • A total of 37 of New York's 82 games with a set total have hit the over (45.1%).
  • The Knicks have entered the game as favorites 64 times this season and won 46, or 71.9%, of those games.
  • This season, New York has won 35 of its 40 games, or 87.5%, when favored by at least -213 on the moneyline.

Cavaliers 2025-26 Betting Trends

  • Cleveland is 34-47-1 against the spread this season.
  • The Cavaliers have a 3-2 record against the spread this year when an underdog by 5.5 points or more.
  • Cleveland has gone over in 40 of its 82 games with a set total (48.8%).
  • The Cavaliers have won 43.8% of the games this season they were the moneyline underdog (7-9).
  • Cleveland has not yet won a game when entering as a moneyline underdog with odds of +177 or longer in four chances.

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Cavaliers vs. Knicks Injury Report

Knicks

Knicks: None

Cavaliers

Cavaliers: None

Cavaliers vs. Knicks Game Time and TV Channel

  • Game day: Thursday, May 21, 2026
  • Game time: 8 p.m. ET
  • TV channel: ESPN
  • Location: New York City, New York
  • Arena: Madison Square Garden

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