Cavaliers vs. Pelicans Predictions, Odds & Stats – March 21

San Antonio Spurs v New Orleans Pelicans

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The Cleveland Cavaliers (43-27) are 4.5-point favorites as they look to extend a three-game road win streak when they visit the New Orleans Pelicans (25-46) on Saturday, March 21, 2026 at Smoothie King Center. The matchup airs at 7 p.m. ET on FDSOH, Gulf Coast Sports, and Pelicans+.

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Listen to the game on Newsradio WTAM 1100

Cavaliers vs. Pelicans Predictions for Saturday

Our computer projection model for this contest calls for a final tally of Cavaliers 120, Pelicans 115.

  • Moneyline Pick: Cavaliers (-195)
  • Total Pick: Under 236.5 (computer predicts 234.4 points)
  • Pick ATS: Cavaliers (-4.5)

Recent Cavaliers vs. Pelicans Matchups

Cavaliers vs Pelicans (Recent Matchups)
Date Favorite Spread Total Favorite Moneyline Underdog Moneyline Result
12/23/2025 Cavaliers -9 248.5 -392 +308 141-118 CLE
11/20/2024 Cavaliers -14.5 216.5 -1075 +686 128-100 CLE
11/6/2024 Cavaliers -6.5 225 -267 +217 131-122 CLE

Cavaliers 2025-26 Betting Trends

  • Cleveland is 30-40-0 against the spread this season.
  • In games this season they were favored by 4.5 points or more, the Cavaliers have a 15-28 record against the spread.
  • Cleveland's games have gone over the point total in 34 out of 71 opportunities (47.9%).
  • The Cavaliers have been favorites in 56 games this season and won 36 (64.3%) of those contests.
  • Cleveland has a record of 27-10, a 73% win rate, when it's favored by -195 or more by oddsmakers this season.

Pelicans 2025-26 Betting Trends

  • New Orleans is 42-28-1 against the spread this season.
  • In games this year in which they were an underdog by 4.5 points or more, the Pelicans have a 21-19-1 record against the spread.
  • A total of 35 of New Orleans' 71 games with a set total have hit the over (49.3%).
  • The Pelicans have won 13 of the 56 games they were the underdog on the moneyline this season (23.2%).
  • When it has played as a moneyline underdog with odds of +162 or longer, New Orleans has gone 6-31 (16.2%).

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Cavaliers vs. Pelicans Injury Report

Cavaliers

Cavaliers:

Craig Porter Jr.: Out (Groin),

Jaylon Tyson: Questionable (Toe),

Tyrese Proctor: Out (Quadricep),

Donovan Mitchell: Questionable (Eye),

Jarrett Allen: Out (Knee)

Pelicans

Pelicans:

Dejounte Murray: Day-To-Day (Achilles),

Bryce McGowens: Day-To-Day (Toe)

Cavaliers vs. Pelicans Game Time and TV Channel

  • Game day: Saturday, March 21, 2026
  • Game time: 7 p.m. ET
  • TV channel: FDSOH, Gulf Coast Sports, and Pelicans+
  • Location: New Orleans, Louisiana
  • Arena: Smoothie King Center

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